Comment on 'Aberrant type 1 immunity drives susceptibility to mucosal fungal infections'
| العنوان: | Comment on 'Aberrant type 1 immunity drives susceptibility to mucosal fungal infections' |
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| المؤلفون: | Nick Willcox, Adrian Hayday, Anthony Meager, Kai Kisand |
| المصدر: | Science. 373 |
| بيانات النشر: | American Association for the Advancement of Science (AAAS), 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Multidisciplinary, medicine.anatomical_structure, Type 1 immunity, business.industry, Feature (computer vision), T cell, Immunology, technology, industry, and agriculture, medicine, Mucous membrane, Chronic mucocutaneous candidiasis, business, medicine.disease |
| الوصف: | Break et al . (Research Articles, 15 January 2021, eaay5731) conclude that T cell overproduction of interferon-γ causes chronic mucocutaneous candidiasis (CMC), a typical early feature of autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy (APECED). This contradicts studies implicating interleukin IL-17 and IL-22 deficiencies as a cause of CMC. We propose that Break et al . have focused on late-arising events rather than more common primary causes of CMC. |
| تدمد: | 1095-9203 0036-8075 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::47dd4d0e8d70b3669602505974d478ef https://doi.org/10.1126/science.abi6235 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi...........47dd4d0e8d70b3669602505974d478ef |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10959203 00368075 |
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