Synthesis, crystal structure, and biological activity of a nickel(II) complex of 2-acetylpyridine N(4)-methylthiosemicarbazone
| العنوان: | Synthesis, crystal structure, and biological activity of a nickel(II) complex of 2-acetylpyridine N(4)-methylthiosemicarbazone |
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| المؤلفون: | Ming-Xue Li, Xian-Feng Zhu, Chun-Ling Chen, Hong-Mei Guo, Jingyang Niu, Dan-Yun Chen |
| المصدر: | Journal of Coordination Chemistry. 63:1546-1554 |
| بيانات النشر: | Informa UK Limited, 2010. |
| سنة النشر: | 2010 |
| مصطلحات موضوعية: | Chemistry, Hydrogen bond, Ligand, chemistry.chemical_element, Crystal structure, chemistry.chemical_compound, Crystallography, Nickel, Monomer, Pyridine, Materials Chemistry, Molecule, Physical and Theoretical Chemistry, 2-Acetylpyridine |
| الوصف: | Nickel complex formulated as Ni(L)2 (L = monodeprotonated ligand corresponding to 2-acetylpyridine N(4)-methylthiosemicarbazone, HL) has been synthesized and characterized by elemental analysis, IR spectra, and single-crystal X-ray diffraction. The complex consists of discrete monomeric molecules with octahedral nickel(II) with two anionic 2-acetylpyridine N(4)-methylthiosemicarbazones as NNS tridentate ligands coordinated to nickel via the pyridine nitrogen, azomethine nitrogen, and sulfur. Hydrogen bonds link the different components to stabilize the crystal structure. Biological studies, carried out in vitro against bacteria, fungi, and the K562 leukemic cell line have shown that the free ligand and complex show distinct differences in biological activity. |
| تدمد: | 1029-0389 0095-8972 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::482a49d164aaf1629172dabf2a23b9d4 https://doi.org/10.1080/00958972.2010.484490 |
| رقم الأكسشن: | edsair.doi...........482a49d164aaf1629172dabf2a23b9d4 |
| قاعدة البيانات: | OpenAIRE |
PDF full text from Publisher | تدمد: | 10290389 00958972 |
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