Tumor MK2 transcript levels are associated with improved response to chemotherapy and patient survival in non-small cell lung cancer
| العنوان: | Tumor MK2 transcript levels are associated with improved response to chemotherapy and patient survival in non-small cell lung cancer |
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| المؤلفون: | Karthik Suresh, Othello Del Rosario, Medha Kallem, Gayatri Singh, Anika Shah, Linda Zheng, Xin Yun, Nicolas M. Philip, Nirupama Putcha, Marni B. McClure, Haiyang Jiang, Franco D’Alessio, Meera Srivastava, Alakesh Bera, Larissa A. Shimoda, Michael Merchant, Madhavi J. Rane, Carolyn E. Machamer, Jason Mock, Robert Hagan, Abigail L. Koch, Naresh M. Punjabi, Todd M. Kolb, Mahendra Damarla |
| المصدر: | Physiological Genomics. 55:168-178 |
| بيانات النشر: | American Physiological Society, 2023. |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | Physiology, Genetics |
| الوصف: | MK2, known to promote caspase-3 nuclear translocation in the execution of apoptosis, is reduced in non-small cell lung cancer cells. In adenocarcinomas of patients, higher MK2 expression is associated with early-stage disease, better clinical response following chemotherapy and independently associated with improved survival. |
| تدمد: | 1531-2267 1094-8341 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::4858e57e9d5950f2a285f4ab23fa97ee https://doi.org/10.1152/physiolgenomics.00155.2022 |
| رقم الأكسشن: | edsair.doi...........4858e57e9d5950f2a285f4ab23fa97ee |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15312267 10948341 |
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