التفاصيل البيبلوغرافية
| العنوان: |
Rapid vacuum sintering: A novel technique for fabricating fluorapatite ceramic scaffolds for bone tissue engineering |
| المؤلفون: |
Julie A. Holloway, Jeffrey D Harless, Ourania-Menti Goudouri, Isabelle Denry |
| المصدر: |
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 106:291-299 |
| بيانات النشر: |
Wiley, 2017. |
| سنة النشر: |
2017 |
| مصطلحات موضوعية: |
Materials science, Fluorapatite, Biomedical Engineering, Sintering, 02 engineering and technology, Bioceramic, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, 0104 chemical sciences, law.invention, Biomaterials, Compressive strength, law, Bioactive glass, visual_art, visual_art.visual_art_medium, Ceramic, Composite material, Crystallization, 0210 nano-technology, Porosity |
| الوصف: |
Macroporous bioceramic scaffolds are often fabricated via the foam replica technique, based on polymeric foam impregnation with a glass slurry, followed by slow heat treatment to allow for drying, polymeric burnout, and sintering of the glass particles. As a consequence, the process is time consuming and complicated by concurrent crystallization of the glass, often leading to incomplete sintering. Our goal was to investigate the effect of heating rate on sintering behavior, architecture, and mechanical properties of fluorapatite-based glass and glass-ceramic scaffolds. Glass scaffolds were prepared and sintered by rapid vacuum sintering (RVS) at 785°C under vacuum at a fast heating rate (55°C/min.) or without vacuum at a slow heating rate (2°C/min.). Two additional groups were further crystallized at 775°C/1 h. XRD confirmed the presence of fluorapatite for crystallized scaffolds. All groups presented interconnected porosity with a pore size in the 500 μm range. Scaffolds produced by RVS exhibited an excellent degree of sintering while scaffolds produced by slow sintering were incompletely sintered. The mean compressive strength was significantly higher for the RVS groups (1.52 ± 0.55 and 1.72 ± 0.61 MPa) compared to the slow-sintered groups (0.54 ± 0.30 and 0.45 ± 0.26 MPa). Meanwhile, the total production time was reduced by more than 12 h by using the RVS technique. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2017. |
| تدمد: |
1552-4973 |
| URL الوصول: |
https://explore.openaire.eu/search/publication?articleId=doi_________::4cf642ee77cbe3c7cf24b3c75ed831e3
https://doi.org/10.1002/jbm.b.33825 |
| حقوق: |
OPEN |
| رقم الأكسشن: |
edsair.doi...........4cf642ee77cbe3c7cf24b3c75ed831e3 |
| قاعدة البيانات: |
OpenAIRE |
