Effect of low-level 1800 MHz radiofrequency radiation on the rat sciatic nerve and the protective role of paricalcitol

التفاصيل البيبلوغرافية
العنوان: Effect of low-level 1800 MHz radiofrequency radiation on the rat sciatic nerve and the protective role of paricalcitol
المؤلفون: Savas Aktas, Meryem İlkay Karagül, Erkan Ozbay, Serap Yalin, Metin Yildirim, Begum Korunur Engiz, Fatma Sogut, Burcu Demirbag, Ulku Comelekoglu, Ayşegül Akar
المصدر: Bioelectromagnetics. 39:631-643
بيانات النشر: Wiley, 2018.
سنة النشر: 2018
مصطلحات موضوعية: Paricalcitol, Nervous system, medicine.medical_specialty, Physiology, Myelinated nerve fiber, Biophysics, medicine.disease_cause, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, medicine, Radiology, Nuclear Medicine and imaging, biology, business.industry, General Medicine, Malondialdehyde, Electrophysiology, Endocrinology, medicine.anatomical_structure, chemistry, Catalase, 030220 oncology & carcinogenesis, biology.protein, Sciatic nerve, business, 030217 neurology & neurosurgery, Oxidative stress, medicine.drug
الوصف: The nervous system is an important target of radiofrequency (RF) radiation exposure since it is the excitable component that is potentially able to interact with electromagnetic fields. The present study was designed to investigate the effects of 1,800 MHz RF radiation and the protective role of paricalcitol on the rat sciatic nerve. Rats were divided into four groups as control, paricalcitol, RF, and RF + paricalcitol. In RF groups, the rats were exposed to 1,800 MHz RF for 1 h per day for 4 weeks. Control and paricalcitol rats were kept under the same conditions without RF application. In paricalcitol groups, the rats were given 0.2 μg/kg/day paricalcitol, three times per week for 4 weeks. Amplitude and latency of nerve compound action potentials, catalase activities, malondialdehyde (MDA) levels, and ultrastructural changes of sciatic nerve were evaluated. In the RF group, a significant reduction in amplitude, prolongation in latency, an increase in the MDA level, and an increase in catalase activity and degeneration in the myelinated nerve fibers were observed. The electrophysiological and histological findings were consistent with neuropathy, and the neuropathic changes were partially ameliorated with paricalcitol administration. Bioelectromagnetics. 39:631-643, 2018. © 2018 Wiley Periodicals, Inc.
تدمد: 0197-8462
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4f9eb801613e46db69e51eeac8e6d1ad
https://doi.org/10.1002/bem.22149
حقوق: CLOSED
رقم الأكسشن: edsair.doi...........4f9eb801613e46db69e51eeac8e6d1ad
قاعدة البيانات: OpenAIRE