Multisensory interactions regulate feeding behavior in Drosophila
| العنوان: | Multisensory interactions regulate feeding behavior in Drosophila |
|---|---|
| المؤلفون: | Jeong Taeg Seo, Seok Jun Moon, Kyunghwa Jeong, Soo Min Oh |
| المصدر: | Proceedings of the National Academy of Sciences. 118 |
| بيانات النشر: | Proceedings of the National Academy of Sciences, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | 0301 basic medicine, Multidisciplinary, Mechanosensation, biology, Multisensory integration, Sensory system, Stimulation, Olfaction, biology.organism_classification, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Proboscis extension reflex, Drosophila melanogaster, Neuroscience, Sensory cue, 030217 neurology & neurosurgery |
| الوصف: | The integration of two or more distinct sensory cues can help animals make more informed decisions about potential food sources, but little is known about how feeding-related multimodal sensory integration happens at the cellular and molecular levels. Here, we show that multimodal sensory integration contributes to a stereotyped feeding behavior in the model organism Drosophila melanogaster Simultaneous olfactory and mechanosensory inputs significantly influence a taste-evoked feeding behavior called the proboscis extension reflex (PER). Olfactory and mechanical information are mediated by antennal Or35a neurons and leg hair plate mechanosensory neurons, respectively. We show that the controlled delivery of three different sensory cues can produce a supra-additive PER via the concurrent stimulation of olfactory, taste, and mechanosensory inputs. We suggest that the fruit fly is a versatile model system to study multisensory integration related to feeding, which also likely exists in vertebrates. |
| تدمد: | 1091-6490 0027-8424 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::51a3ce9eaeee18d86e66b23fc9b79421 https://doi.org/10.1073/pnas.2004523118 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi...........51a3ce9eaeee18d86e66b23fc9b79421 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10916490 00278424 |
|---|