Clinical Characteristics, Laboratory Features, and Outcomes of 151 Pediatric Patients With COVID-19 and MIS-C: A Single-center Study in the Northwest of Iran
| العنوان: | Clinical Characteristics, Laboratory Features, and Outcomes of 151 Pediatric Patients With COVID-19 and MIS-C: A Single-center Study in the Northwest of Iran |
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| المؤلفون: | Mahmoud Samadi, Mahboobeh Azadi, Amir Saeed, Akbar Molaei, Shahram Abdoli Oskouie, Shamsi Ghaffari, Ahmad Jamei Khosroshahi, Sara Kaveh |
| المصدر: | Archives of Pediatric Infectious Diseases. |
| بيانات النشر: | Briefland, 2023. |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | Infectious Diseases, Pediatrics, Perinatology and Child Health |
| الوصف: | Background: To date, multiple outbreaks of coronavirus disease 2019 (COVID-19) have been reported. Moreover, a wide spectrum of multiple organ involvements has been reported. Objectives: This study aimed to describe and compare the clinical characteristics, laboratory features, and outcomes of pediatric patients with COVID-19 and Multisystem Inflammatory Syndrome of Children (MIS-C). Methods: This cohort retrospective study was performed on patients under 18 years admitted with a diagnosis of COVID-19 and MIS-C in a pediatric referral center in the northwest of Iran from March 2020 to June 2021. This study included the data obtained from three time points, including on admission, 1 week, and 3 months after admission. Results: In this study, 151 patients with a mean age of 5.3 ± 4.1 years were enrolled, out of whom 51.7% and 48.3% were in COVID-19 and MIS-C groups, respectively. Fever was observed in 64.9% of the patients. In the third-month follow-up, there was no abnormality in the neurologic, respiratory, or gastrointestinal systems. For most patients with cardiovascular involvement, normal ventricular and valvar function, and coronary arteries were obtained in follow-up. Approximately one-third of the subjects were admitted to the pediatric intensive care unit (PICU). Neonates, those with cardiac involvement and underlying disease, were at a higher risk for PICU admission (P < 0.001). Moreover, six patients died. Conclusions: Although irreversible post-COVID-19 organ involvement is uncommon among pediatric patients, routine and preplanned follow-up programs play an important role in achieving satisfactory outcomes. |
| تدمد: | 2322-1836 2322-1828 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::5365e8e2a7a3af97dca4c2e80f9264f0 https://doi.org/10.5812/pedinfect-132819 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi...........5365e8e2a7a3af97dca4c2e80f9264f0 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 23221836 23221828 |
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