Rapid Assembly of Oligosaccharides: Total Synthesis of a Glycosylphosphatidylinositol Anchor ofTrypanosoma brucei
| العنوان: | Rapid Assembly of Oligosaccharides: Total Synthesis of a Glycosylphosphatidylinositol Anchor ofTrypanosoma brucei |
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| المؤلفون: | Daniel K. Baeschlin, Virginie Charbonneau, André R. Chaperon, Luke G. Green, Eric Walther, Steven V. Ley, Ulrich Lücking |
| المصدر: | Angewandte Chemie International Edition. 37:3423-3428 |
| بيانات النشر: | Wiley, 1998. |
| سنة النشر: | 1998 |
| مصطلحات موضوعية: | chemistry.chemical_classification, biology, Chemistry, Stereochemistry, Dihydropyran, Convergent synthesis, Total synthesis, General Chemistry, Trypanosoma brucei, Oligosaccharide, biology.organism_classification, Desymmetrization, Catalysis, carbohydrates (lipids), chemistry.chemical_compound, lipids (amino acids, peptides, and proteins), Glycosylphosphatidylinositol anchor, Reactivity (chemistry) |
| الوصف: | Six building blocks, six reaction steps: The recently developed innovative methodology facilitated the convergent synthesis of the complex oligosaccharide core 1 (shown here with protecting groups) for the total synthesis of a glycosylphosphatidylinositol (GPI) anchor. The key factors are the tuning of the reactivity of the building blocks by using 1,2-diacetal protecting groups and the desymmetrization of glycerol and myo-inositol with a chiral bis(dihydropyran). |
| تدمد: | 1521-3773 1433-7851 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::53eb4e145abd56839d7f00be4de95902 https://doi.org/10.1002/(sici)1521-3773(19981231)37:24<3423::aid-anie3423>3.0.co;2-i |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........53eb4e145abd56839d7f00be4de95902 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15213773 14337851 |
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