(+)- and (−)-Preuisolactone A: A Pair of Caged Norsesquiterpenoidal Enantiomers with a Tricyclo[4.4.01,6.02,8]decane Carbon Skeleton from the Endophytic Fungus Preussia isomera
| العنوان: | (+)- and (−)-Preuisolactone A: A Pair of Caged Norsesquiterpenoidal Enantiomers with a Tricyclo[4.4.01,6.02,8]decane Carbon Skeleton from the Endophytic Fungus Preussia isomera |
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| المؤلفون: | Ikuro Abe, Hai-Li Chen, Lu-Lin Xu, Yuan Gao, Ping Hai, Xiao-Long Yang, Chuandong Xie |
| المصدر: | Organic Letters. 21:1078-1081 |
| بيانات النشر: | American Chemical Society (ACS), 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Preussia isomera, biology, 010405 organic chemistry, Stereochemistry, Organic Chemistry, chemistry.chemical_element, Stereoisomerism, Decane, Endophytic fungus, 010402 general chemistry, biology.organism_classification, 01 natural sciences, Biochemistry, 0104 chemical sciences, chemistry.chemical_compound, chemistry, Physical and Theoretical Chemistry, Enantiomer, Micrococcus luteus, Antibacterial activity, Carbon |
| الوصف: | A pair of enantiomeric norsesquiterpenoids, (+)- and (−)-preuisolactone A (1) [(+)-1 and (−)-1)] featuring an unprecedented tricyclo[4.4.01,6.02,8]decane carbon scaffold were isolated from Preussia isomera. Their structures were determined by spectroscopic and computed methods and X-ray crystallography. Compounds (+)-1 and (−)-1 are two rare naturally occurring sesquiterpenoidal enantiomers. A plausible biosynthetic pathway for 1 is proposed. Additionally, (±)-1 exhibited remarkable antibacterial activity against Micrococcus luteus with an MIC value of 10.2 μM. |
| تدمد: | 1523-7052 1523-7060 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::55347faa788ab1031f37878215fdabab https://doi.org/10.1021/acs.orglett.8b04123 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........55347faa788ab1031f37878215fdabab |
| قاعدة البيانات: | OpenAIRE |
Find this issue from the American Chemical Society | تدمد: | 15237052 15237060 |
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