Acute interleukin-6 modulates key enzymes involved in prefrontal cortex and hippocampal amyloid precursor protein processing
| العنوان: | Acute interleukin-6 modulates key enzymes involved in prefrontal cortex and hippocampal amyloid precursor protein processing |
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| المؤلفون: | Daniel M. Marko, Michael S. Finch, Alex J. T. Yang, Laura N. Castellani, Willem T. Peppler, David C. Wright, Rebecca E. K. MacPherson |
| المصدر: | Journal of Applied Physiology. 134:1115-1123 |
| بيانات النشر: | American Physiological Society, 2023. |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | Physiology, Physiology (medical) |
| الوصف: | It is becoming evident that exercise modulates APP processing and can reduce amyloid-beta (Aβ) peptide production. Our data help to explain this phenomenon by highlighting IL-6 as an exercise-induced factor that lowers pathological APP processing. These results also highlight brain regional differences in response to acute IL-6. |
| تدمد: | 1522-1601 8750-7587 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::5c8dce3d069816314330f57855e37143 https://doi.org/10.1152/japplphysiol.00520.2022 |
| رقم الأكسشن: | edsair.doi...........5c8dce3d069816314330f57855e37143 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15221601 87507587 |
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