To observe the effects of the use of incinerator bottom ash (IBA) on open-graded asphalt concrete (OGAC), natural fine aggregates are partially replaced by IBA in OGAC. The results indicate that the use of IBA helps improve the adhesive force between asphalt and aggregates. The stability and indirect tensile strength of OGAC are effectively improved by the use of IBA as a replacement material. The natural fine aggregate content in the OGAC is 25%. The results indicate that 80% of natural fine aggregates could be replaced by IBA and demonstrate the feasibility of using IBA in OGAC in engineering applications.