High-Resolution Bacterial Cytological Profiling Reveals Intrapopulation Morphological Variations upon Antibiotic Exposure
العنوان: | High-Resolution Bacterial Cytological Profiling Reveals Intrapopulation Morphological Variations upon Antibiotic Exposure |
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المؤلفون: | Thanadon Samernate, Htut Htut Htoo, Joseph Sugie, Warinthorn Chavasiri, Joe Pogliano, Vorrapon Chaikeeratisak, Poochit Nonejuie |
المصدر: | Antimicrobial Agents and Chemotherapy. 67 |
بيانات النشر: | American Society for Microbiology, 2023. |
سنة النشر: | 2023 |
مصطلحات موضوعية: | Pharmacology, Infectious Diseases, Pharmacology (medical) |
الوصف: | Phenotypic heterogeneity is crucial to bacterial survival and could provide insights into the mechanism of action (MOA) of antibiotics, especially those with polypharmacological actions. Although phenotypic changes among individual cells could be detected by existing profiling methods, due to the data complexity, only population average data were commonly used, thereby overlooking the heterogeneity. |
تدمد: | 1098-6596 0066-4804 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::5eed2e6de0671bd143c9a1e3cbc8aa23 https://doi.org/10.1128/aac.01307-22 |
حقوق: | CLOSED |
رقم الأكسشن: | edsair.doi...........5eed2e6de0671bd143c9a1e3cbc8aa23 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 10986596 00664804 |
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