Effects of Probiotic Lactobacilli plantarum in Treatment of Experimentally Induced Periodontal Disease in Rabbits
| العنوان: | Effects of Probiotic Lactobacilli plantarum in Treatment of Experimentally Induced Periodontal Disease in Rabbits |
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| المؤلفون: | Yeganeh Mehrani, Hossien Kazemi Mehrjerdi, Azin Tavakoli, Reyhaneh Shafieian, Amir Salari |
| المصدر: | Journal of Veterinary Dentistry. :089875642311631 |
| بيانات النشر: | SAGE Publications, 2023. |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | General Veterinary |
| الوصف: | The aim of this study was to evaluate the therapeutic effects of probiotic Lactobacillus plantarum in experimentally induced periodontal disease in rabbits. The incisor teeth of 24 rabbits were scaled under general anesthesia. Two weeks later, silk ligatures were placed at the gingival margin of the incisor teeth to induce periodontal disease. After confirming the presence of periodontal disease by periodontal probing four weeks later, incisor mucogingival flaps were created and gingival pocket lavage and debridement was performed. The rabbits were randomly divided into four groups. Group 1: Control; Group 2: Microencapsulated form of the probiotic; Group 3: Planktonic form of the probiotic; and Group 4: Biofilm form of the probiotic. The rabbits were euthanized eight weeks later, and gingival connective tissue and epithelium were resected for histopathological and histomorphometric evaluation. The results showed that the rate of epithelial regeneration was lower and bone regeneration was significantly higher in the treatment groups compared to the Control group. The highest level of bone regeneration was in Group 2 (Microencapsulated probiotic). There was no significant difference in bone regeneration observed between the biofilm and planktonic probiotic groups. This study showed that applying the probiotic Lactobacillus plantarum in microencapsulated form improved bone regeneration in experimentally induced periodontal disease in rabbits. |
| تدمد: | 2470-4083 0898-7564 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::5fc4919b9b5cd1a4f01a72009e26ce11 https://doi.org/10.1177/08987564231163193 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........5fc4919b9b5cd1a4f01a72009e26ce11 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 24704083 08987564 |
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