Micellar electrokinetic chromatography of tri aza aromatic ligand compounds of iron (II): Influence of bile salt type on enantiomeric separation
| العنوان: | Micellar electrokinetic chromatography of tri aza aromatic ligand compounds of iron (II): Influence of bile salt type on enantiomeric separation |
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| المؤلفون: | Kathryn A. Woody, Said Elshihabi, Michelle M. Bushey, Kelly D. Black, Jennefer K. Sutton, John A. Burke |
| المصدر: | ELECTROPHORESIS. 22:3771-3777 |
| بيانات النشر: | Wiley, 2001. |
| سنة النشر: | 2001 |
| مصطلحات موضوعية: | chemistry.chemical_classification, Clinical Biochemistry, Quinoline, Salt (chemistry), Buffer solution, Biochemistry, Micellar electrokinetic chromatography, Analytical Chemistry, Lepidine, chemistry.chemical_compound, chemistry, Hexafluorophosphate, Glycochenodeoxycholic acid, Organic chemistry, Enantiomer, Nuclear chemistry |
| الوصف: | Micellar electrokinetic chromatography is used with a variety of bile salt micelles to separate the enantiomers of bis(8-((pyridine-2-methylene)amino)quinoline)iron(II) hexafluorophosphate, Fe(PMAQ)2(PF6)2; bis(8-((pyridine-2-methylene)amino)lepidine iron(II) hexafluorophosphate, Fe(PMAL)2(PF6)2; and bis(1-(2-pyridinyl)ethylidine)-8-aminoquinoline iron(II) hexafluorophosphate, Fe(PEAQ)2(PF6)2. The influence of ten different bile salts on the resolution of each pair of enantiomers is investigated. Significant changes in resolution are seen depending upon the bile salt used. The dihydroxy bile salts are superior to the trihydroxy bile salts in terms of resolution, and the taurine or glycine conjugated bile salts yield better results than the unconjugated bile salts. Resolution for most enantiomers is maximized in a buffer solution containing 10-15% acetone and employing either taurochenodeoxycholic or glycochenodeoxycholic acid as the bile salt. Evidence for the separation of the corresponding Fe(III) complexes is presented. |
| تدمد: | 1522-2683 0173-0835 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::6172c142be2cfdd02799c5580d723c4a https://doi.org/10.1002/1522-2683(200109)22:17<3771::aid-elps3771>3.0.co;2-j |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........6172c142be2cfdd02799c5580d723c4a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15222683 01730835 |
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