Simple desensitization protocol for multiple myeloma patients with lenalidomide‐induced skin rash: Case series
| العنوان: | Simple desensitization protocol for multiple myeloma patients with lenalidomide‐induced skin rash: Case series |
|---|---|
| المؤلفون: | Masao Hagihara, Shin Ohara, Takeo Yasu, Tomiyuki Sugi, Morihiro Inoue, Tomoyuki Uchida, Mitsuo Mita |
| المصدر: | Journal of Clinical Pharmacy and Therapeutics. 46:1792-1795 |
| بيانات النشر: | Hindawi Limited, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Pharmacology, medicine.medical_specialty, business.industry, medicine.medical_treatment, Drug holiday, medicine.disease, 030226 pharmacology & pharmacy, Rash, Dermatology, 03 medical and health sciences, 0302 clinical medicine, medicine, Pharmacology (medical), In patient, 030212 general & internal medicine, Dosing, medicine.symptom, Adverse effect, business, Multiple myeloma, Desensitization (medicine), Lenalidomide, medicine.drug |
| الوصف: | What is known and objective Skin rash is one of the typical side effects of lenalidomide (LEN) treatment. Desensitization therapies have been reported to be effective in patients with severe skin rash caused by LEN. However, they have proved impractical due to the complexity of the protocols. Case summaries We present 5 patients who developed severe LEN-induced skin rash. The five patients received our simple, slow desensitization protocol, and all were re-administered LEN with no adverse reaction. What is new and conclusion Our simpler and slow desensitization protocol, which desensitizes the patients without reducing the effect of LEN, includes drug holidays, similar to the usual LEN dosing schedule, and moreover is recommended as a treatment option especially for elderly patients with no housemate to help with medical management. |
| تدمد: | 1365-2710 0269-4727 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::651c52eb54bd91cc2378b9324ce2eb90 https://doi.org/10.1111/jcpt.13433 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........651c52eb54bd91cc2378b9324ce2eb90 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13652710 02694727 |
|---|