Analysis of NAD and NAD-Dependent Protein Deacetylation in Mouse Tissues
| العنوان: | Analysis of NAD and NAD-Dependent Protein Deacetylation in Mouse Tissues |
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| المؤلفون: | Maria Svetlova, Mikhail Khodorkovskiy, Konstantin A. Shabalin, E. A. Gubareva, L. V. Solovjeva, Andrey Nikiforov, A. V. Panchenko, Alexander Yakimov, O. S. Mudrak, Kirill Nerinovski, Veronika Kulikova |
| المصدر: | Cell and Tissue Biology. 12:491-495 |
| بيانات النشر: | Pleiades Publishing Ltd, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | 0301 basic medicine, Nad dependent, Cell Biology, Nicotinamide adenine dinucleotide, Biology, Mitochondrion, 03 medical and health sciences, Cytosol, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, Biochemistry, chemistry, Acetylation, 030220 oncology & carcinogenesis, NAD+ kinase, Protein deacetylation |
| الوصف: | Nicotinamide adenine dinucleotide (NAD) plays a key role in the vital metabolic and regulatory processes in mammals. Disturbance of the NAD level regulation is associated with the development of such serious diseases as pellagra, neurodegenerative and cardiovascular disorders, diabetes, cancer and others. This paper presents an experimental approach that allows to determine the amount of NAD+ in mouse tissues using NMR spectroscopy, as well as the level of NAD+-dependent deacetylation of proteins in the cytosol and mitochondria. |
| تدمد: | 1990-5203 1990-519X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::6c21f0c612525bd00dd5d91d0ab98f6b https://doi.org/10.1134/s1990519x18060123 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........6c21f0c612525bd00dd5d91d0ab98f6b |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 19905203 1990519X |
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