Knochenmarktransplantationen bei Panmyelopathie und Leukämien: unter besonderer Berücksichtigung gnotobiotischer Maßnahmen
| العنوان: | Knochenmarktransplantationen bei Panmyelopathie und Leukämien: unter besonderer Berücksichtigung gnotobiotischer Maßnahmen |
|---|---|
| المؤلفون: | E. Kuwert, F. Schüning, K. Henneberg, Hossam K. Mahmoud, M. Bamberg, E. Scherer, O. Wetter, S. Öhl, U. Quast, Ulrich W. Schaefer, Hans Grosse-Wilde, W. Alberti, D. Hantschke, G. Linzenmeier, L. D. Leder, E. Haralambie, Ch. Schmidt, W. Luboldt, M. R. Nowrousian, Reinhard Becher, H. J. Richter, G. Schmitt |
| المصدر: | DMW - Deutsche Medizinische Wochenschrift. 109:1909-1913 |
| بيانات النشر: | Georg Thieme Verlag KG, 2008. |
| سنة النشر: | 2008 |
| مصطلحات موضوعية: | medicine.medical_specialty, business.industry, Incidence (epidemiology), First remission, General Medicine, Chronic myeloid leukaemia, Gastroenterology, Transplantation, hemic and lymphatic diseases, Internal medicine, medicine, PANMYELOPATHY, Interstitial pneumonia, Myeloid leukaemia, business, Cause of death |
| الوصف: | Bone-marrow transplantations were performed in 71 patients, 11 with panmyelopathy, 17 with recurrence of acute leukaemia, 25 with acute leukaemia and remission, 18 with chronic myeloid leukaemia. The transplantation was allogenic in 67, autologous in 2, isologous in 2. Eight patients each survived in the panmyelopathy and chronic myeloid leukaemia groups. In the group of patients with acute leukaemia only one patient of those in a recurrence survived the transplantation for several years, but after 6 years there was another recurrence. Of the 20 patients with acute myeloid leukaemia who received the transplantation during their first remission, 11 are still alive. Retransplantation because of the recurrence was employed in one case each of acute and chronic myeloid leukaemia. Main cause of death was interstitial pneumonia with an overall risk of 23%. Only 5% of patients developed severe acute graft-versus-host reaction, grades III-IV. The low incidence of this reaction is possibly due to the strict gnotobiotic measures which in most of the patients led to decontamination of the intestinal tract. |
| تدمد: | 1439-4413 0012-0472 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::6d6b5a65c4aa92e87aafccbfb18ed800 https://doi.org/10.1055/s-2008-1069477 |
| رقم الأكسشن: | edsair.doi...........6d6b5a65c4aa92e87aafccbfb18ed800 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14394413 00120472 |
|---|