Comparison of clinical outcomes and accuracy of electrode placement between robot-assisted and conventional deep brain stimulation of the subthalamic nucleus: a single-center study
| العنوان: | Comparison of clinical outcomes and accuracy of electrode placement between robot-assisted and conventional deep brain stimulation of the subthalamic nucleus: a single-center study |
|---|---|
| المؤلفون: | Adélaïde Nunes, Julien Berthiller, Teodor Danaila, Andrei Brinzeu, Shams Ribault, Patrick Mertens, Stéphane Thobois, Gustavo Polo, Chloé Laurencin, E. Simon |
| المصدر: | Acta Neurochirurgica. 163:1327-1333 |
| بيانات النشر: | Springer Science and Business Media LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, Parkinson's disease, Neurology, Deep brain stimulation, medicine.medical_treatment, Single Center, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, medicine, Neuroradiology, medicine.diagnostic_test, business.industry, Interventional radiology, medicine.disease, nervous system diseases, Subthalamic nucleus, surgical procedures, operative, nervous system, Anesthesia, Surgery, Neurology (clinical), Neurosurgery, business, therapeutics, 030217 neurology & neurosurgery |
| الوصف: | Several surgical methods are used for deep brain stimulation (DBS) of the subthalamic nucleus (STN) in Parkinson’s disease (PD). This study aimed to compare clinical outcomes and electrode placement accuracy after robot-assisted (RAS) versus frame-based stereotactic (FSS) STN DBS in Parkinson’s disease. In this single-center open-label study, we prospectively collected data from 48 consecutive PD patients who underwent RAS (Neuromate®; n = 20) or FSS (n = 28) STN DBS with the same MRI-based STN targeting between October 2016 and December 2018 in the university neurological hospital of Lyon, France. Clinical variables were assessed before and 1 year after surgery. The number of electrode contacts within the STN was determined by merging post-operative CT and pre-operative MRI using Brainlab® GUIDE™XT software. One year after surgery, the improvement of motor manifestations (p = 0.18), motor complications (p = 0.80), and quality of life (p= 0.30) and the reduction of dopaminergic treatment (p = 0.94) and the rate of complications (p = 0.99) were similar in the two groups. Surgery duration was longer in the RAS group (p = 0.0001). There was no difference in the number of electrode contacts within the STN. This study demonstrates that RAS and FSS STN DBS for PD provide similar clinical outcomes and accuracy of electrode placement. |
| تدمد: | 0942-0940 0001-6268 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::718354538bb88b1d24f777a717774918 https://doi.org/10.1007/s00701-021-04790-7 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........718354538bb88b1d24f777a717774918 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 09420940 00016268 |
|---|