Chlorhexidine Showers are Associated With a Reduction in Surgical Site Infection Following Spine Surgery: An Analysis of 4266 Consecutive Surgeries
| العنوان: | Chlorhexidine Showers are Associated With a Reduction in Surgical Site Infection Following Spine Surgery: An Analysis of 4266 Consecutive Surgeries |
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| المؤلفون: | Amy Nichols, Dean Chou, Sanjay S. Dhall, Catherine Liu, Praveen V. Mummaneni, Taemin Oh, Caleb S. Edwards, Catherine Miller, Christopher P. Ames, Henry C. Skrehot, Alvin Y. Chan, Sravani Kondapavulur, Aaron J. Clark, Andrew K Chan, Simon G Ammanuel |
| المصدر: | Neurosurgery. 85:817-826 |
| بيانات النشر: | Ovid Technologies (Wolters Kluwer Health), 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | medicine.medical_specialty, Multivariate analysis, business.industry, Chlorhexidine, Subgroup analysis, Odds ratio, Preoperative care, Confidence interval, Surgery, 03 medical and health sciences, 0302 clinical medicine, 030220 oncology & carcinogenesis, Cohort, medicine, Neurology (clinical), Complication, business, 030217 neurology & neurosurgery, medicine.drug |
| الوصف: | Background Surgical site infection (SSI) is a common complication following spinal surgery. Prevention is critical to maintaining safe patient care and reducing additional costs associated with treatment. Objective To determine the efficacy of preoperative chlorhexidine (CHG) showers on SSI rates following fusion and nonfusion spine surgery. Methods A mandatory preoperative CHG shower protocol was implemented at our institution in November 2013. A cohort comparison of 4266 consecutive patients assessed differences in SSI rates for the pre- and postimplementation periods. Subgroup analysis was performed on the type of spinal surgery (eg, fusion vs nonfusion). Data represent all spine surgeries performed between April 2012 and April 2016. Results The overall mean SSI rate was 0.4%. There was no significant difference between the pre- (0.7%) and postimplementation periods (0.2%; P = .08). Subgroup analysis stratified by procedure type showed that the SSI rate for the nonfusion patients was significantly lower in the post- (0.1%) than the preimplementation group (0.7%; P = .02). There was no significant difference between SSI rates for the pre- (0.8%) and postimplementation groups (0.3%) for the fusion cohort (P = .21). In multivariate analysis, the implementation of preoperative CHG showers were associated with significantly decreased odds of SSI (odds ratio = 0.15, 95% confidence interval [0.03-0.55], P Conclusion This is the largest study investigating the efficacy of preoperative CHG showers on SSI following spinal surgery. In adjusted multivariate analysis, CHG showering was associated with a significant decrease in SSI following spinal surgery. |
| تدمد: | 1524-4040 0148-396X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::719a139223ced6de714d91e2f895b3ef https://doi.org/10.1093/neuros/nyy568 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi...........719a139223ced6de714d91e2f895b3ef |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15244040 0148396X |
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