ChemInform Abstract: Knowledge Based Prediction of Ligand Binding Modes and Rational Inhibitor Design for Kinase Drug Discovery
| العنوان: | ChemInform Abstract: Knowledge Based Prediction of Ligand Binding Modes and Rational Inhibitor Design for Kinase Drug Discovery |
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| المؤلفون: | John P. Mallamo, Joseph M. Salvino, Torsten Herbertz, Douglas A. Pippin, Arup K. Ghose |
| المصدر: | ChemInform. 39 |
| بيانات النشر: | Wiley, 2008. |
| سنة النشر: | 2008 |
| مصطلحات موضوعية: | chemistry.chemical_compound, chemistry, Drug discovery, Kinase, medicine, Imatinib, General Medicine, Pharmacology, Benzamide, medicine.drug |
| الوصف: | toward kinase inhibitor discovery, with the result that several kinase inhibitors have been approved as drugs since 2001. The commercial success of imatinib (N-(4-methyl-3-(4-(pyridin-3yl)pyrimidin-2-ylamino)phenyl)-4-((4-methylpiperazin-1-l)methyl)benzamide) has provided a clear incentive for the continued pursuit of kinase inhibitor design. |
| تدمد: | 1522-2667 0931-7597 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::7259ef73433538f3d0a4e33a7e5d96ff https://doi.org/10.1002/chin.200850260 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........7259ef73433538f3d0a4e33a7e5d96ff |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15222667 09317597 |
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