Host-mediated biofilm forming promotes post-graphene pathogen expansion via graphene micron-sheet
| العنوان: | Host-mediated biofilm forming promotes post-graphene pathogen expansion via graphene micron-sheet |
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| المؤلفون: | Jun Liu, Jinghuan Tian, Wei Zhang, Bo Luan, Kun Yang, Ke Liu, Wei Qu, Likui Wang, Junhui Ji |
| المصدر: | Frontiers of Materials Science. 14:221-231 |
| بيانات النشر: | Springer Science and Business Media LLC, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Materials science, biology, Graphene, Graphene derivatives, Biofilm, Potential candidate, Nanotechnology, 02 engineering and technology, Periplasmic space, 010402 general chemistry, 021001 nanoscience & nanotechnology, biology.organism_classification, 01 natural sciences, 0104 chemical sciences, law.invention, law, General Materials Science, 0210 nano-technology, Bacterial outer membrane, Pathogen, Bacteria |
| الوصف: | Graphene is a potential candidate for applications in biomedical field. It is inevitable that graphene is in contact with the ubiquitous bacterial environment. More attention has been paid to the antimicrobial activity of graphene derivatives (graphene oxide, reduced graphene oxide) than the interaction between graphene and bacteria. Herein, we explore interaction between graphene micron-sheet and bacteria from micro (gene expression) and macro (colonies) perspectives. Results demonstrate that graphene micron-sheet accelerates the biofilm forming thus promoting pathogen expansion toward both Gram-negative bacteria E. coli and Gram-positive bacteria S. aureus. The graphene micron-sheet acts as a “habitat” for increasing bacterial attachment and biofilm forming. For E. coli, graphene micron-sheet, firstly changes the integrity of periplasmic and outer membrane components, then makes membrane-associated and cell division genes increased, and finally promotes bacterial proliferation; For S. aureus, graphene micron-sheet can accelerate biofilm forming and develop bacterial expansion owing to the regulation of the quorum-sensing system and global regulatory proteins. The work can shed new light on the range of possible mode of actions, developing a better understanding of the capabilities of graphene micron-structures. |
| تدمد: | 2095-0268 2095-025X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::72e7cd3d0fb8cb2403a099c84d7d0da3 https://doi.org/10.1007/s11706-020-0498-4 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........72e7cd3d0fb8cb2403a099c84d7d0da3 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 20950268 2095025X |
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