Comparison of Postoperative, In-Hospital Outcomes After Complete Repair of Tetralogy of Fallot Between 22q11.2 Deletion Syndrome and Trisomy 21
| العنوان: | Comparison of Postoperative, In-Hospital Outcomes After Complete Repair of Tetralogy of Fallot Between 22q11.2 Deletion Syndrome and Trisomy 21 |
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| المؤلفون: | Isabella Zaniletti, Timothy E. Nissen, Parthak Prodhan, Elijah H. Bolin, R. Thomas Collins, Paul M. Seib, Lawrence E. Greiten |
| المصدر: | Pediatric Cardiology. 43:290-300 |
| بيانات النشر: | Springer Science and Business Media LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, business.industry, Postoperative complication, Retrospective cohort study, Odds ratio, medicine.disease, Confidence interval, Cardiac surgery, Internal medicine, Pediatrics, Perinatology and Child Health, medicine, Tetralogy, Cardiology and Cardiovascular Medicine, Trisomy, business, Tetralogy of Fallot |
| الوصف: | 22q11.2 deletion syndrome (22q11) and trisomy 21 (T21) are frequently associated with tetralogy of Fallot (TOF). We hypothesized that there are differences in postoperative length of stay (LOS) and occurrence of postoperative interventions after complete repair of TOF when comparing children with 22q11 to those with T21. Using the Pediatric Health Information System, we performed a retrospective cohort study of patients who underwent complete repair of TOF from 2004 to 2019. Three groups were identified: 22q11, T21, and controls (those without a coded genetic syndrome). Outcomes were postoperative LOS and composite occurrence (yes/no) of at least one postoperative intervention. Bivariate and multivariate comparisons were made among groups; odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using the control group as the comparator. There were 6924 subjects (n = 493 22q11, n = 455 T21, n = 5976 controls). In bivariate analysis, 22q11 was associated with a longer LOS compared to T21 (OR 2.37 [2.16, 2.60] vs. 1.25 [1.12, 1.39], p |
| تدمد: | 1432-1971 0172-0643 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::7445f703b6d2ebf321dd69fcc10f16a1 https://doi.org/10.1007/s00246-021-02683-1 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........7445f703b6d2ebf321dd69fcc10f16a1 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 14321971 01720643 |
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