Positional Sleep Apnea Among Regional and Remote Australian Population and Simulated Positional Treatment Effects

التفاصيل البيبلوغرافية
العنوان: Positional Sleep Apnea Among Regional and Remote Australian Population and Simulated Positional Treatment Effects
المؤلفون: Subash S. Heraganahally, Xin Yi Er, Himanshu Garg, Timothy Howarth
المصدر: Nature and Science of Sleep. 12:1123-1135
بيانات النشر: Informa UK Limited, 2020.
سنة النشر: 2020
مصطلحات موضوعية: education.field_of_study, medicine.medical_specialty, Supine position, medicine.diagnostic_test, business.industry, medicine.medical_treatment, Population, Sleep apnea, Polysomnography, medicine.disease, respiratory tract diseases, Obstructive sleep apnea, 03 medical and health sciences, Behavioral Neuroscience, 0302 clinical medicine, 030228 respiratory system, Internal medicine, medicine, Continuous positive airway pressure, education, Airway, business, Body mass index, 030217 neurology & neurosurgery, Applied Psychology
الوصف: Purpose To assess the prevalence of positional sleep apnea (POSA) and its predictors in patients diagnosed to have obstructive sleep apnea (OSA) in the regional and remote population of the Northern Territory of Australia over a two-year study period (2018 and 2019). Patients and Methods Of the total 1463 adult patients who underwent a diagnostic polysomnography (PSG), 946 patients were eligible to be included in the study, of them, 810 consecutive patients with OSA (Apnea-Hypopnea Index (AHI) ≥ 5) who slept >4 h and had ≥30 min sleep in both supine and lateral positions were assessed. Patients were considered to have POSA if supine AHI to lateral AHI ratio ≥2. The likely comparative impact of use of continuous positive airway therapy (CPAP) or positional therapy (PT) on disease severity was evaluated using model simulation. Results A total of 495/810 (61%) patients had POSA, the majority were males (68% vs 60%, p=0.013) and non-Indigenous Australians (93% vs 87%, p=0.004). POSA patients were younger (mean difference 2.23 years (95% CI 0.27, 4.19)), less obese (BMI mean difference 3.06 (95% CI 2.11, 4.01)), demonstrated less severe OSA (p < 0.001) and a greater proportion reported alcohol consumption (72% vs 62%, p=0.001) as compared to those with non-POSA. Using the simulation model, if patients with POSA use PT two-thirds (323/495, 65%) would obtain significant improvement of their OSA severity, with one in five (92/495, 19%) displaying complete resolution. Comparing this to simulated CPAP therapy, where the majority (444/495, 90%) will show significant improvement, and one-third (162/495, 33%) will display complete resolution. Conclusion POSA needs to be routinely recognised and positional therapy integrated in practice especially in the remote regions and in the developing world when effective methods are in place to monitor positional therapy.
تدمد: 1179-1608
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::74cad79309024b2f1d1a648522ec7638
https://doi.org/10.2147/nss.s286403
حقوق: OPEN
رقم الأكسشن: edsair.doi...........74cad79309024b2f1d1a648522ec7638
قاعدة البيانات: OpenAIRE