Introduction: The aim of this study will be to compare the socioeconomic status & quality of life in Cleft & non-cleft patients up to 18 years old children in Rajasthan. Materials and methods: The sample consisted of hundred cleft patients in the study group and hundred patients in the control group of under 18 years of age. A questionnaire survey was designed for CLP cases that came to the Darshan Dental college and Hospital, Udaipur, were included in the study. These patients were compared with fty matched patients (control group) who had no CLP. A questionnaire was designed and pretested, and informed consent from the cases and careers was taken for both the groups. The questionnaire was answered individually, only once, at a private place. Student's t-test was used to compare the means between cleft group and the control group. Results: The literacy status of the parents, their socioeconomic status, and occupation had a signicant interrelation for the occurrence of CLP (P < 0.05) as compared with the controls. According to the parents' perception on the WHOQoL-Bref of children with and without cleft lip and palate, oral health of children with oral clefts had a statistically signicant impact on WHOQoL-Bref. Conclusion: The group comparison revealed that the cleft lip and palate negatively impacted on WHOQoL of children and their parents. Education about oral health must be given repeatedly