Synthesis of N-Substituted-2-Aminothiazolo[4,5-b]pyrazines by Tandem Reaction of o-Aminohalopyrazines with Isothiocyanates

التفاصيل البيبلوغرافية
العنوان: Synthesis of N-Substituted-2-Aminothiazolo[4,5-b]pyrazines by Tandem Reaction of o-Aminohalopyrazines with Isothiocyanates
المؤلفون: Young-Dae Gong, Gee-Hyung Lee, Se Hun Kwak
المصدر: Bulletin of the Korean Chemical Society. 33:4271-4274
بيانات النشر: Korean Chemical Society, 2012.
سنة النشر: 2012
مصطلحات موضوعية: chemistry.chemical_classification, Solvent, Base (chemistry), chemistry, Cascade reaction, Yield (chemistry), Organic chemistry, General Chemistry
الوصف: with a stronger base such as NaOH, KOH and LiOH,afforded 2a in moderate yield, except with LiOH (Table 1,entries 3-5). The addition of CuI was deteriorative (Table 1,entry 6). Different solvents were screened in order to increasethe yield (Table 1, entries 7-10). The best result was obtainedwhen DMSO was used as a solvent (Table 1, entry 10). Thereaction time was reduced by using more base equivalentwith a similar yield (Table 1, entry 11). The yield wasdiminished at 100
تدمد: 0253-2964
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7a841b5347343be782a7c086ace081a8
https://doi.org/10.5012/bkcs.2012.33.12.4271
حقوق: OPEN
رقم الأكسشن: edsair.doi...........7a841b5347343be782a7c086ace081a8
قاعدة البيانات: OpenAIRE