Two Outbreaks of Severe Respiratory Disease in Nursing Homes Associated with Rhinovirus

التفاصيل البيبلوغرافية
العنوان: Two Outbreaks of Severe Respiratory Disease in Nursing Homes Associated with Rhinovirus
المؤلفون: Cynthia G. Whitney, Maria Lucia Tondella, Robert F. Benson, Marc Fischer, Dean D. Erdman, Lauri A. Hicks, W. Lanier Thacker, Daniel R. Feikin, Mària E. Moll, Brendan Flannery, Xiaoyan Lu, Angela J. Peck, Larry J. Anderson, Phyllis H. Britz, Colin W. Shepard
المصدر: Journal of the American Geriatrics Society. 54:284-289
بيانات النشر: Wiley, 2006.
سنة النشر: 2006
مصطلحات موضوعية: medicine.medical_specialty, Respiratory tract infections, business.industry, Medical record, Respiratory disease, Outbreak, medicine.disease, medicine.disease_cause, respiratory tract diseases, Pneumonia, Internal medicine, Cohort, Etiology, Medicine, Geriatrics and Gerontology, Rhinovirus, business, Intensive care medicine
الوصف: Objectives: To characterize illness and identify the etiology for two nursing home outbreaks of respiratory illness. Design: Multisite outbreak investigations; cohort. Setting: Two nursing homes in Pennsylvania. Participants: Facility A residents (n=170), Facility B residents (n=124), and employees (n=91). Measurements: Medical records for Facility A and B residents were reviewed, and employees from Facility B self-administered a questionnaire to identify risk factors for illness. Serological, oropharyngeal, and nasopharyngeal specimens were collected for both outbreaks, and testing for respiratory pathogens was performed. Results: In Facility A, 40 (24%) of 170 residents were identified with respiratory illness; 13 (33%) case-patients had radiographically confirmed pneumonia, 15 (38%) were taken to a hospital, and two (5%) died. Of 10 specimens collected from symptomatic Facility A case-patients, four (40%) tested positive using reverse transcription polymerase chain reaction for rhinovirus. In Facility B, 77 (62%) of 124 residents had respiratory illness, and 40 (52%) had radiographically confirmed pneumonia; 12 (16%) case-patients were hospitalized, and five (6%) died. Of 19 respiratory specimens collected from symptomatic Facility B case-patients, six (32%) were positive for rhinovirus; one was from an employee. Five (50%) of 10 rhinovirus-positive cases in both outbreaks had clinical and radiographic evidence of pneumonia. Conclusion: These investigations suggest that rhinoviruses may be an underrecognized cause of respiratory outbreaks in nursing homes, capable of causing pneumonia and perhaps death.
تدمد: 1532-5415
0002-8614
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7c2de12b619f7930106d755cd5dbd1a5
https://doi.org/10.1111/j.1532-5415.2005.00529.x
حقوق: CLOSED
رقم الأكسشن: edsair.doi...........7c2de12b619f7930106d755cd5dbd1a5
قاعدة البيانات: OpenAIRE