Early Intervention with Impedance-guided Heart Failure Management Improves Long-term Outcome: Insights from the IMPEDANCE-HF Trial
العنوان: | Early Intervention with Impedance-guided Heart Failure Management Improves Long-term Outcome: Insights from the IMPEDANCE-HF Trial |
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المؤلفون: | Michael Shochat, Daniel Kapustin, Marat Fudim, Mark Kazatsker, Ilia Kleiner, Jean Weinstein, Gurusher Panjrath, Guy Rozen, Ariel Roguin, Simcha Meisel |
المصدر: | Medical Research Archives. 10 |
بيانات النشر: | Knowledge Enterprise Journals, 2022. |
سنة النشر: | 2022 |
الوصف: | Background: Lung-impedance (LI) guided treatment of heart failure (HF) patients was shown to improve clinical outcomes. Objectives: To perform a post-hoc analysis of the IMPEDANCE-HF extended trial in order to explore the mechanism underlying the improved outcome of the LI-guided compared with conventional therapy of HF patients. Methods: The study included 290 HF patients with LVEF≤ 45% randomized 1:1 to LI-guided or conventional therapy. The normal LI (NLI), representing the dry lung status, was calculated upon enrollment. The level of pulmonary congestion (LPC) was represented by ΔLIR= [(measured LI/NLI)-1] × 100%. Results: There were 11473 outpatient visits in the LI-guided group and 10245 visits in the control group during follow-up, or 15.5 and 15.9 visits/patient×year, respectively (p=0.74). The LI-guided patients were on average less congested during follow-up than those in the control group (by 20 %, p |
تدمد: | 2375-1924 2375-1916 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::7c8c0073597154dfc8ccc41d606c8f05 https://doi.org/10.18103/mra.v10i5.2766 |
رقم الأكسشن: | edsair.doi...........7c8c0073597154dfc8ccc41d606c8f05 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 23751924 23751916 |
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