| الوصف: |
The National Agricultural Biotechnology Information Cen-ter (NABIC) constructed an agricultural biology-based in-frastructure and developed a biological information- based database. The major functions of the NABIC are focused on biotechnological developments for agricul-tural bioinformatics and providing a web-based service to construct bioinformatics workflows easily, such as protein function prediction and genome systems biology programs. The NABIC has concentrated on the func-tional genomics of major crops, building an integrated biotechnology database for agro-biotech information that focuses on the proteomics of major agricultural re-sources, such as rice, Chinese cabbage, rice Ds-tagging lines, and microorganisms.Keywords: biotechnology, database, genome, informa-tion model, web service Introduction The genomic information from humans to microorga-nisms is rapidly increasing in the 21st century. Today, technological advances in the fields of genomic se-quencing and protein structure have led to the develop-ment of genomic, proteomic, microarray, and functional genomic data (Ann, 2008). Biological databases have been established to optimize scientific exploitation of the explosion of data within bioinformatics. Bioinfor-matics databases and tools provide analyzed results to understand the basic principles of molecular inter-actions and systemic functional behaviors of organisms (Russ, 2007). With the continuous elaboration of bio-informatics tools around the world, various databases have been constructed at bioinformatics centers with gene expression, genetic marker, microarray gene fam-ily, protein prediction, and functional genetic information (Kim et al., 2010). The National Center for Biotechnology Information (NCBI, http://www.ncbi.nlm.nih.gov/) pro-vides analysis and retrieval resources for the data in GenBank and other biological data that are made avail-able through the NCBI website (Sayers et al., 2008). GRAMENE (http://www.gramene.org/) provides genomic information for Oryza sativa using a genomic browser (Youens-Clark et al., 2008). In Korea, biological information-based models have been developed with a knowledge-based approach for functional gene prediction, gene data-mining using mi-croarray, and protein-protein interaction networks (Kim et al., 2008). The Korean Bioinformation Center (http:// www.kobic.re.kr/) is a national research center for bio-informatics that plays a key role in various areas, such as genomics, proteomics, systems biology, and person-alized medicine. The Biology Research Information Cen-ter (http://bric.postech.ac.kr/) and Biotech Policy Resear-ch Center (http://www.bioin.or.kr/) support the govern-ment in setting up biotechnology information and all of the relevant information provided in the portal site. The NABIC (http://nabic.naas.go.kr/) has constructed an agri-cultural biology-based infrastructure and has provided comprehensive agricultural biological research informa-tion. Major functions are focused on biotechnological developments for agricultural bioinformatics. |
