التفاصيل البيبلوغرافية
| العنوان: |
Long noncoding RNAs in autoimmune diseases |
| المؤلفون: |
Zhiyan Nie, Hong Zheng, Yueling Jin, Fei Xu, Lei Jin |
| المصدر: |
Journal of Biomedical Materials Research Part A. 107:468-475 |
| بيانات النشر: |
Wiley, 2018. |
| سنة النشر: |
2018 |
| مصطلحات موضوعية: |
Materials science, Disease occurrence, Multiple sclerosis, 0206 medical engineering, Metals and Alloys, Biomedical Engineering, 02 engineering and technology, 021001 nanoscience & nanotechnology, medicine.disease, Bioinformatics, 020601 biomedical engineering, Biomaterials, Immune system, Potential biomarkers, Rheumatoid arthritis, Psoriasis, Ceramics and Composites, medicine, Human genome, 0210 nano-technology |
| الوصف: |
With the completion of the human genome project and further development of high-throughput genomic technologies, interest in long noncoding RNAs (lncRNAs), which are defined as non-protein-coding RNAs at least 200 nucleotides in length, has strongly increased, and lncRNAs have become a major research direction. Increasing evidence demonstrates that lncRNAs are closely related to human growth and development and to disease occurrence via various mechanisms. lncRNAs also play crucial roles in the differentiation and activation of immune cells, and their relationships with human autoimmune diseases have received increasing attention. The development of biotechnology has led to the gradual discovery of many potential lncRNA functions. In this review, we discuss various lncRNAs that have been implicated in different human autoimmune diseases, focusing on their clinical applications as potential biomarkers and therapeutic targets in the pathologies of diverse human autoimmune diseases. © 2018 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 107A: 468-475, 2019. |
| تدمد: |
1549-3296 |
| URL الوصول: |
https://explore.openaire.eu/search/publication?articleId=doi_________::883441b23f319c4e958139f9bf9b388a
https://doi.org/10.1002/jbm.a.36562 |
| حقوق: |
CLOSED |
| رقم الأكسشن: |
edsair.doi...........883441b23f319c4e958139f9bf9b388a |
| قاعدة البيانات: |
OpenAIRE |
