Efficacy of Modified Wuzhuyu Decoction Granule (加减吴茱萸汤 颗粒剂) for Migraine Patients with Cold and Stasis Obstructing Meridian Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial
| العنوان: | Efficacy of Modified Wuzhuyu Decoction Granule (加减吴茱萸汤 颗粒剂) for Migraine Patients with Cold and Stasis Obstructing Meridian Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial |
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| المؤلفون: | Yong Zhang, Da-yong Ma, Ke-gang Cao, Yihuai Zou, Li-hua Yu, Hong-wei Liu, Cai-hong Fu |
| المصدر: | Chinese Journal of Integrative Medicine. 24:409-414 |
| بيانات النشر: | Springer Science and Business Media LLC, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | medicine.medical_specialty, Visual analogue scale, business.industry, Placebo-controlled study, Decoction, General Medicine, Traditional Chinese medicine, Placebo, medicine.disease, Surgery, law.invention, 03 medical and health sciences, 0302 clinical medicine, Meridian (perimetry, visual field), Complementary and alternative medicine, Randomized controlled trial, Migraine, law, Anesthesia, medicine, Pharmacology (medical), 030212 general & internal medicine, business, 030217 neurology & neurosurgery |
| الوصف: | To study the efficacy of modified Wuzhuyu Decoction Granule (加减吴茱萸汤颗粒, MWDG) in the treatment of migraine patients with cold and stasis obstructing meridian syndrome. This study was a randomized, double-blind, placebo-controlled trial. A total of 78 migraine patients with cold and stasis obstructing meridian syndrome were recruited and randomly assigned by a ratio of 2:1 into a treatment group (51 cases) and a placebo group (27 cases). Patients in the treatment group were treated with MWDG while placebo granules were applied in the control group. The treatment course lasted for 12 weeks with a follow-up of 4 weeks. The primary outcome measures included frequency and days of migraine attacks and the secondary outcome measures were analgesics consumption and visual analogue scale (VAS) scores. All outcome assessments were conducted respectively at baseline, the 4th, 8th and 12th week, and the end of follow-up. In the treatment group, significant decrease in frequency of migraine attacks were observed since the 4th week and that of analgesics consumption since the 8th week (both P 0.05). MWDG was probably effective in the treatment of migraine especially for alleviating pain intensity. Furthermore, MWDG could reduce the frequency of migraine attacks and analgesics consumption sooner than the placebo. |
| تدمد: | 1993-0402 1672-0415 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::8c006aeb18b7db7baf597d3f8a11a915 https://doi.org/10.1007/s11655-017-2547-5 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........8c006aeb18b7db7baf597d3f8a11a915 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 19930402 16720415 |
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