Abstract T MP56: Immediate Post-operative Serum Blood Urea Nitrogen is Strongly Associated with Early Post-surgical Stroke Risk in Cardiac Surgical Patients
| العنوان: | Abstract T MP56: Immediate Post-operative Serum Blood Urea Nitrogen is Strongly Associated with Early Post-surgical Stroke Risk in Cardiac Surgical Patients |
|---|---|
| المؤلفون: | Martinson K Arnan, Tyken Hsieh, Joseph Yeboah, Alain Bertoni, Gregory Burke, Zainab Bahrainwala, Maura Grega, William Baumgartner, Rebecca Gottesman |
| المصدر: | Stroke. 46 |
| بيانات النشر: | Ovid Technologies (Wolters Kluwer Health), 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Advanced and Specialized Nursing, Neurology (clinical), Cardiology and Cardiovascular Medicine |
| الوصف: | Objective: To identify perioperative risk factors that are associated with post-operative stroke risk after all cardiac surgical procedures at a large tertiary hospital. Methods: Among 5498 adults aged 18-90 years who underwent cardiac surgery at Johns Hopkins Hospital from 2005-2010, we identified 180 cases who suffered a stroke within 10 days post-operatively. An equal number of controls were randomly selected and frequency-matched for sex and age-band to cases. Univariate and multivariate logistic regression analyses were performed to ascertain risk factors for post-operative stroke. Results: Emergent surgery (OR 3.04, 95% CI 1.80- 5.10), current smoking (OR 1.97, 95% CI 1.29- 3.00), peripheral vascular disease (OR 2.80, 95% CI 1.41-5.53), and previous stroke with residual paralysis (OR 4.27 95% CI 1.18-15.38) were associated with increased stroke risk. Pre-operative blood pressures were higher in cases than in controls (p post-operative BUN was higher in cases than in controls (p< 0.0001). In multivariable logistic regression (adjusted for pre-operative hematocrit, post-operative creatinine, acute myocardial infarction and low ejection fraction), post-operative BUN was associated with increased odds of stroke (OR 2.4 per 25% increase in BUN, p Conclusion: In these analyses we have identified factors that are associated with post-operative stroke for all types of cardiac surgery. Awareness of these exposures may improve stroke risk assessment. |
| تدمد: | 1524-4628 0039-2499 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::8f3312255b39fa1809f948c174c8be8c https://doi.org/10.1161/str.46.suppl_1.tmp56 |
| رقم الأكسشن: | edsair.doi...........8f3312255b39fa1809f948c174c8be8c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15244628 00392499 |
|---|