Abstract 15046: Arrhythmia Profile in Female Atrial Fibrillation Patients With versus Without Autoimmune Disorders
| العنوان: | Abstract 15046: Arrhythmia Profile in Female Atrial Fibrillation Patients With versus Without Autoimmune Disorders |
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| المؤلفون: | John Burkhardt, Gerald Gallinghouse, Faiz M. Baqai, Sanghamitra Mohanty, Rodney Horton, Angel Mayedo, Bryan MacDonald, Joseph G. Gallinghouse, Carola Gianni, Domenico G. Della Rocca, Chintan Trivedi, Luigi Di Biase, Andrea Natale, Amin Al-Ahmad, Mohamed Bassiouny |
| المصدر: | Circulation. 142 |
| بيانات النشر: | Ovid Technologies (Wolters Kluwer Health), 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | medicine.medical_specialty, genetic structures, business.industry, Physiology (medical), Internal medicine, medicine, Cardiology, Atrial fibrillation, Inflammation, medicine.symptom, Cardiology and Cardiovascular Medicine, medicine.disease, business |
| الوصف: | Background: Autoimmune disorders (AuID) are pro-inflammatory conditions and inflammation is known to promote atrial fibrillation (AF). We evaluated the arrhythmia profile in female AF patients with vs without AuID. Methods: Consecutive female patients undergoing their first catheter ablation at our center were included in the analysis and divided into two groups; group 1: with AuID (n=192) and group 2: no AuID (n=2324). All received PV isolation + isolation of left atrial posterior wall and superior vena cava. Additionally, non-PV triggers identified by isoproterenol-challenge were ablated in all.Patients were included in group 1 if they had an established diagnosis of Type 1 Diabetes (DM), rheumatoid arthritis (RA), Lupus, inflammatory bowel disease (IBD), Psoriasis, Sjogren syndrome, Grave’s disease or Celiac disease. Results: Baseline characteristics of the study groups are provided in table 1. Most prevalent AuID were DM (56, 29%), RA (52, 27%), Lupus (35, 18.2%) and IBD (40, 20.8%). Patients with AuID were significantly younger and more had non-paroxysmal AF. They also had larger LA diameter and lower LVEF compared to the group with no AuID. Significantly higher number of non-PV triggers were detected in group 1 patients (149 (77.6%) vs 883 (38%), p Conclusion: Women with autoimmune diseases experienced AF at an earlier age with significantly more non-paroxysmal AF compared to those without. However, similar ablation success was observed in both groups that could be attributed to the ablation strategy including all detectable non-PV triggers. Table |
| تدمد: | 1524-4539 0009-7322 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::913cc95956c6f796ec4781f2efea82a4 https://doi.org/10.1161/circ.142.suppl_3.15046 |
| رقم الأكسشن: | edsair.doi...........913cc95956c6f796ec4781f2efea82a4 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15244539 00097322 |
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