Accessing Novel Process Windows in a High-Temperature/Pressure Capillary Flow Reactor
| العنوان: | Accessing Novel Process Windows in a High-Temperature/Pressure Capillary Flow Reactor |
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| المؤلفون: | Tahseen Razzaq, C. O. Kappe, Toma N. Glasnov |
| المصدر: | Chemical Engineering & Technology. 32:1702-1716 |
| بيانات النشر: | Wiley, 2009. |
| سنة النشر: | 2009 |
| مصطلحات موضوعية: | Claisen rearrangement, Boiling point, Chemistry, Capillary action, General Chemical Engineering, Thermodynamics, General Chemistry, Flow chemistry, Microreactor, Industrial and Manufacturing Engineering, Supercritical fluid, Volumetric flow rate, Bar (unit) |
| الوصف: | High-temperature/pressure organic synthesis can be performed under continuous flow conditions in a stainless steel microtubular flow reactor capable of achieving temperatures of 350 °C and 200 bar (X-Cube Flash™). Using these extreme experimental environments, the Claisen rearrangement of allyl phenyl ether together with the ensuing rearrangement chemistry of the resulting 2-allylphenol product was investigated. Reaction optimization was performed by changing the temperatures, pressures and flow rates “on-the-fly”. In addition, the high-temperature/pressure flow system allowed the study of these transformations in low boiling point solvents in or near their supercritical state. In general, the chemistry optimized under high-temperature microwave batch conditions could be successfully translated to a scalable flow regime. |
| تدمد: | 1521-4125 0930-7516 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::968ea2f09d3ff98eab2ec54874be9077 https://doi.org/10.1002/ceat.200900272 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........968ea2f09d3ff98eab2ec54874be9077 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15214125 09307516 |
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