Increased sympathetic activity can cause repolarization instability in athlete's heart

التفاصيل البيبلوغرافية
العنوان: Increased sympathetic activity can cause repolarization instability in athlete's heart
المؤلفون: Miklós Tóth, Zs. Major, Anna Udvardy, Zsolt Komka, Gábor Pavlik, Emese Trájer, Anna Protzner, Edit Bosnyák
المصدر: Interventional Medicine and Applied Science. 3:134-137
بيانات النشر: Akademiai Kiado Zrt., 2011.
سنة النشر: 2011
مصطلحات موضوعية: medicine.medical_specialty, Sympathetic nervous system, biology, Athletes, business.industry, Athlete's heart, General Medicine, medicine.disease, biology.organism_classification, Sudden death, Sudden cardiac death, medicine.anatomical_structure, Internal medicine, medicine, Catecholamine, Cardiology, Repolarization, Increased Sympathetic Activity, business, human activities, medicine.drug
الوصف: Sudden cardiac death (SCD) of athletes usually occurs during warm-up or shortly after training. At this point sympathetic tone is still elevated but oxygen demand does not differ from resting levels. It is supposed not to have a primarily ischemic origin but most likely relates to repolarization abnormalities which can be associated with intracellular cAMP level caused by increased sympathetic tone. The mediators of sympathetic nervous system are the catecholamines (epinephrin, norepinephrin). Measuring QT-dispersion can show the repolarization's inhomogeneity. 27 elite soccer players, 28 triathletes and 29 non-trained control person took part in our study. It was recorded cardiac ultrasound, an ECG and taken blood before and after exercise. We found significantly higher QT-dispersion and catecholamines in soccer players compared to the triathletes and the controls. However the soccer players did not show larger athlete's heart than the triathletes. After exercise the increased repolarization inhomogeneity persisted in soccer players, but in triathletes it decreased. Increased sympathetic tone in athletes can enhance arrhythmia propensity. Our data may explain why the soccer players die of sudden cardiac death most commonly in Europe.
تدمد: 2061-5094
2061-1617
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::98c31475168d9f6ef58032fcd822eaff
https://doi.org/10.1556/imas.3.2011.3.13
حقوق: OPEN
رقم الأكسشن: edsair.doi...........98c31475168d9f6ef58032fcd822eaff
قاعدة البيانات: OpenAIRE