Rapid Access to 1-Benzyl 2-Substituted Piperazines: Application to the Synthesis of 1-Benzyl-2-difluoromethyl-Piperazine
| العنوان: | Rapid Access to 1-Benzyl 2-Substituted Piperazines: Application to the Synthesis of 1-Benzyl-2-difluoromethyl-Piperazine |
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| المؤلفون: | Daniele Donati, Francesca Cardullo, Carmela Napolitano, Stefano Manfredini, Alfredo Paio, Manuela Borriello |
| المصدر: | Synthetic Communications. 41:2031-2035 |
| بيانات النشر: | Informa UK Limited, 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | Piperazine, chemistry.chemical_compound, chemistry, Organic Chemistry, Rapid access, Organic chemistry, Combinatorial chemistry |
| الوصف: | A rapid and efficient synthesis of 1-benzyl-2-difluoromethyl-piperazine is herein described. The new pathway has the advantage of avoiding orthogonal protection at the two piperazine nitrogen atoms; therefore it is suitable for access to several 1-benzyl 2-substituted piperazines starting from the simple commercially available N,N′-dibenzylethylendiamine. |
| تدمد: | 1532-2432 0039-7911 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::9d03e38c7789a8fa1ea9c58b8881b3e2 https://doi.org/10.1080/00397911.2010.491171 |
| رقم الأكسشن: | edsair.doi...........9d03e38c7789a8fa1ea9c58b8881b3e2 |
| قاعدة البيانات: | OpenAIRE |
PDF full text from Publisher | تدمد: | 15322432 00397911 |
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