The junctional adhesion molecule-А (JAM-A) and pathogenetic mechanisms of essential hypertension
| العنوان: | The junctional adhesion molecule-А (JAM-A) and pathogenetic mechanisms of essential hypertension |
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| المؤلفون: | A. V. Stepanov, B. I. Kuznik, E. S. Guseva, I. V. Fine, Y. N. Smolyakov, S. O. Davydov |
| المصدر: | "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 24:293-302 |
| بيانات النشر: | Arterialnaya Gipertenziya, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | business.industry, Adhesion, 030204 cardiovascular system & hematology, Essential hypertension, medicine.disease, humanities, Cell biology, 03 medical and health sciences, 0302 clinical medicine, Internal Medicine, Medicine, Cardiology and Cardiovascular Medicine, business, 030217 neurology & neurosurgery |
| الوصف: | Recent studies demonstrated an important role of the junctional adhesion molecule-A (JAM-A) in the pathogenesis of essential hypertension. Our studies showed higher content of JAM-A in women with essential hypertension. Also hypertensive women have higher levels of very low–density lipoprotein (VLDL), higher atherogenic index and lower concentrations of estrogen, progesterone and prolactin, indicating an increased risk of atherosclerosis and premature aging. By the laser speckle showed that the hemodynamic indices considerably change in essential hypertension. The levels of JAM-A correlate with blood pressure, lipids and hemodynamic indices, both in healthy subjects and in women with essential hypertension. The data demonstrate the importance of JAM-A in the pathogenesis of essential hypertension. |
| تدمد: | 2411-8524 1607-419X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::9fca00000a1c91aa261c0056ed064e6e https://doi.org/10.18705/1607-419x-2018-24-3-293-302 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi...........9fca00000a1c91aa261c0056ed064e6e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 24118524 1607419X |
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