Effect of CMC Concentration on Cell Growth Behavior of PVA/CMC Hydrogel
| العنوان: | Effect of CMC Concentration on Cell Growth Behavior of PVA/CMC Hydrogel |
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| المؤلفون: | Deuk Yong Lee, Jung In Yoon, Ji-Yeon Shin, Yo-Seung Song |
| المصدر: | Macromolecular Research. 28:813-819 |
| بيانات النشر: | Springer Science and Business Media LLC, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | musculoskeletal diseases, Pore size, Materials science, Polymers and Plastics, General Chemical Engineering, macromolecular substances, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Polyvinyl alcohol, chemistry.chemical_compound, Materials Chemistry, medicine, integumentary system, Cell growth, Organic Chemistry, Drug release rate, technology, industry, and agriculture, Cell growth rate, musculoskeletal system, 021001 nanoscience & nanotechnology, 0104 chemical sciences, Carboxymethyl cellulose, Compressive strength, chemistry, Self-healing hydrogels, 0210 nano-technology, medicine.drug, Nuclear chemistry |
| الوصف: | Polyvinyl alcohol (PVA)/carboxymethyl cellulose (CMC) hydrogels containing various CMC concentration of 2 to 10 wt% are prepared using cyclic freezing/thawing and subsequent γ-ray irradiation to evaluate the effect of CMC content on cell growth rate of the hydrogels. A 3-D porous network structure is successfully formed via physical and chemical crosslinking. The pore size and the metronidazole drug release rate of the PVA/CMC hydrogels increase with raising the CMC concentration from 2 to 10 wt%, however, the structural integrity is severely damaged. The highest compressive strength of 99.2 ± 9.6 kPa and the fastest cell growth determined by scratch assay and enzyme-linked immunosorbent assay are observed for the irradiated PVA/6 wt% CMC hydrogels, indicating that they are highly suitable for wound dressing requiring fast regeneration. |
| تدمد: | 2092-7673 1598-5032 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::a387bf2788e5361052e9bc187e19eeac https://doi.org/10.1007/s13233-020-8106-0 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........a387bf2788e5361052e9bc187e19eeac |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 20927673 15985032 |
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