4-(4-Acethylphenyl)-3-hydroxycoumarin in the Synthesis of Nitrogen-containing Heterocycles with a Neoflavonoid Moiety
| العنوان: | 4-(4-Acethylphenyl)-3-hydroxycoumarin in the Synthesis of Nitrogen-containing Heterocycles with a Neoflavonoid Moiety |
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| المؤلفون: | O. V. Skrypska, Roman Lytvyn, Kh. Ye. Pitkovych, Mykola D. Obushak, P. I. Yagodinets, O. V. Rusnak |
| المصدر: | Russian Journal of Organic Chemistry. 55:1145-1152 |
| بيانات النشر: | Pleiades Publishing Ltd, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Pyrimidine, 010405 organic chemistry, Chemistry, Organic Chemistry, Quinoline, Ring (chemistry), 01 natural sciences, Medicinal chemistry, 0104 chemical sciences, Neoflavonoid, chemistry.chemical_compound, Thiourea, Pyridine, Moiety, Thiazole |
| الوصف: | 4-(4-Acetylphenyl)-3-hydroxy-2H-chromen-2-one has been prepared by the reaction of (4-acetylbenzene)diazonium chloride with 3-hydroxy-2H-chromen-2-one under Meerwein reaction conditions. The reactions of 4-(4-bromoacetylphenyl)-3-hydroxy-2H-chromen-2-one with pyridine, 4-methylpyridine, quinolone, and benzo[f]quinoline gave quaternary salts, and the reactions of the same bromo derivative with thioacetamide, thiourea, pyridine-2-amine, pyrimidin-2-amine, and thiazol-2-amine provided corresponding thiazole, imidazo[1,2-a]pyridine, imidazo[1,2-a]pyrimidine, and imidazo[2,1-b]thiazole derivatives. The reactions of 4-(4-bromoacetylphenyl)-3-hydroxy-2H-chromen-2-one with thiosemicarbazide and aromatic aldehydes involve thiazole ring formation, leading finally to corresponding hydrazones. It was established that 4-(4-acetylphenyl)- and 4-[4-(2-bromoacetyl)phenyl]-3-hydroxy-2H-chromen-2-ones can be used in three-component reactions to form a thiazole ring. |
| تدمد: | 1608-3393 1070-4280 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::a407f26886d7253fa78e376801d63b2b https://doi.org/10.1134/s107042801908013x |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........a407f26886d7253fa78e376801d63b2b |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 16083393 10704280 |
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