Synthesis, Crystal Structure and Inhibitory Activities of 2-(N-Tert-Butoxycarbonylamino)Pyridine Derivatives
| العنوان: | Synthesis, Crystal Structure and Inhibitory Activities of 2-(N-Tert-Butoxycarbonylamino)Pyridine Derivatives |
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| المؤلفون: | Bao-Tong Li, Ming-Yu Zhao, Xu-Liang Nie, Xugen Shi, Yun-Lian Shi, Da-Yong Peng, Ming-Zhu Shi, Tao Huang, Xue-Xiang Ren |
| المصدر: | Journal of Chemical Crystallography. 51:155-160 |
| بيانات النشر: | Springer Science and Business Media LLC, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Pyricularia, biology, Chemistry, Stereochemistry, Biological activity, General Chemistry, Crystal structure, Carbon-13 NMR, 010402 general chemistry, 010403 inorganic & nuclear chemistry, Condensed Matter Physics, Alternaria, biology.organism_classification, 01 natural sciences, 0104 chemical sciences, chemistry.chemical_compound, Crystallography, Pyridine, Proton NMR, Organometallic chemistry |
| الوصف: | 2-(N-tert-butoxycarbonylamino) pyridine and 2-(N-tert-butoxycarbonylamino)-3-methylpyridine were synthesized in a one-step method using either 2-aminopyridine or 2-amino-3-methyphyridine with tert-butylcarbonyl anhydride as the starting materials. The products were characterized by single-crystal X-ray diffraction, 1H NMR, 13C NMR, and HRMS. The biological activity of the two compounds against five fungi was determined. 2-(N-tert-butoxycarbonylamino) pyridine has more than 50% inhibitory activity against Pyricularia oryzae, Colletotrichum gloeosporioides, and Alternaria alternate. In addition, the inhibitory activity of 2-(N-tert-butoxycarbonylamino)-3-methylpyridine against Alternaria alternate reached 67.69%. Two 2-BOC aminopyridine derivatives were synthesized and structurally characterized by 1H NMR, 13C NMR, HRMS analysis and X-ray crystal diffraction. The inhibitory activity both compounds was studied. |
| تدمد: | 1572-8854 1074-1542 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::a739b01533ada962a0ec3edfb0fb2ea6 https://doi.org/10.1007/s10870-020-00833-6 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........a739b01533ada962a0ec3edfb0fb2ea6 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 15728854 10741542 |
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