The present study was conducted to examine the clinical manifestations of broilers suffering from tibial dyschondroplasia (TD) on growth performance, drumstick parameters, breast meat quality, and serum biochemical parameters. A total of 200 Arbor Acre broiler chickens were randomly allocated into two groups: control (basal diet) and TD group (basal diet supplemented with 50 mg/kg of thiram). Each group consisted of 4 replicates (25 chickens per replicate). The experiment lasted for 14 days. Results showed that TD chickens exhibited abnormal foraging behavior and resting position that caused a reduction in feed intake, daily weight gain and final body weight. Compared with the control group, the weight and length of drumstick in TD chicken group was significantly decreased (p 0.05). In conclusion, the TD has adverse effect on the overall growth performance, drumstick parameters, breast meat quality, and some serum biochemical parameters of broilers. Moreover, decreased breast muscle quality was strongly correlated with leg problems in the tibia.