Successful Treatment of Intra-Arterial Peplomycin Infusion for Recurrent Oral Florid Papillomatosis
| العنوان: | Successful Treatment of Intra-Arterial Peplomycin Infusion for Recurrent Oral Florid Papillomatosis |
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| المؤلفون: | Madoka Takafuji, Atsushi Tanemura, Manabu Fujimoto, Yuma Hanaoka, Mari Wataya-Kaneda, Eiji Kiyohara |
| المصدر: | Journal of Cosmetics, Dermatological Sciences and Applications. :223-227 |
| بيانات النشر: | Scientific Research Publishing, Inc., 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | medicine.medical_specialty, business.industry, Verrucous Lesion, Etretinate, medicine.disease, Surgery, stomatognathic diseases, medicine.anatomical_structure, Infusion therapy, Tongue, Medicine, Oral lichen planus, Oral florid papillomatosis, Peplomycin, Oral mucosa, business, medicine.drug |
| الوصف: | A 56-year-old woman had noticed the erosion of oral mucosa and tongue 8 years ago. The mucosal lesions had been initially diagnosed as oral lichen planus and resistant to various treatments with prednisolone, etretinate and mizoribine and so on. One year ago, rapidly growing verrucous lesion occurred on her upper lip. Although we administered intralesional radiation therapy, the tumor recurred and new whitish lesions on the buccal mucosa and hard palate occurred 9 months after treatment. We confirmed an anatomical blood supply to the tumors by a fluorescent real-time imaging system and subsequently administered the intra-arterial infusion of peplomycin through retrograde catheters from bilateral superficial temporal arteries under the final diagnosis as oral florid papillomatosis (OFP). The tumors were dramatically shrunk and did not recur 16 months after treatment. OFP is known as clinically multiple whitish and verrucous lesions over the oral cavity and lip and a subtype of SCC with high differentiation. We suppose that an intra-arterial infusion therapy of peplomycin should be considered as the curative treatment for OFP. |
| تدمد: | 2161-4512 2161-4105 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::a91e409b4010ab54d191f35fc885faab https://doi.org/10.4236/jcdsa.2019.93019 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi...........a91e409b4010ab54d191f35fc885faab |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 21614512 21614105 |
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