Pulmonary tuberculosis: could tumor markers CA 15-3 and CA 125 be useful for diagnosis and evaluation of response to therapy?
| العنوان: | Pulmonary tuberculosis: could tumor markers CA 15-3 and CA 125 be useful for diagnosis and evaluation of response to therapy? |
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| المؤلفون: | Azema Abd El-Rahman, Ehsan Rizk, Ehab Badran Rakha, Niveen Saudy, Walaa Othman Elshabrawy |
| المصدر: | Comparative Clinical Pathology. 27:107-114 |
| بيانات النشر: | Springer Science and Business Media LLC, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | 0301 basic medicine, medicine.medical_specialty, Tuberculosis, endocrine system diseases, business.industry, 030106 microbiology, Isoniazid, Case-control study, CA 15-3, Drug resistance, medicine.disease, Gastroenterology, female genital diseases and pregnancy complications, Group B, Pathology and Forensic Medicine, 03 medical and health sciences, Blood serum, Internal medicine, Immunology, medicine, Anatomy, business, Ethambutol, medicine.drug |
| الوصف: | Diagnosis and treatment evaluation of pulmonary tuberculosis (PTB) are time-consuming, so a non-conventional approach should be considered. Our study investigates the utility of CA125 and CA15-3 in differentiation of PTB from other pulmonary infections and prediction of response to antituberculous drugs. A prospective case control study was carried out on 69 patients: group A: 42 PTB and group B (control): 27 non-PTB patients. All patients were subjected to clinical, radiological, microbiological, and quantitative measurement of serum levels of CA125 and CA15-3 by ELIZA at time of diagnosis. Gp-A patients were ZN and culture positive for TB. Antituberculous susceptibility of Mycobacterium isolates was performed by proportional method. Two months after therapy, ZN examination and CA125 and CA15-3 levels were performed. Pretreatment levels of CA125 and CA15-3 in TB patients were significantly higher than both control groups (P = |
| تدمد: | 1618-565X 1618-5641 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::acf3c27e456aa67ae42e19c1107bab12 https://doi.org/10.1007/s00580-017-2559-3 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........acf3c27e456aa67ae42e19c1107bab12 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 1618565X 16185641 |
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