JDQ443, a Structurally Novel, Pyrazole-Based, Covalent Inhibitor of KRASG12C for the Treatment of Solid Tumors

التفاصيل البيبلوغرافية
العنوان: JDQ443, a Structurally Novel, Pyrazole-Based, Covalent Inhibitor of KRASG12C for the Treatment of Solid Tumors
المؤلفون: Edwige Lorthiois, Marc Gerspacher, Kim S. Beyer, Andrea Vaupel, Catherine Leblanc, Rowan Stringer, Andreas Weiss, Rainer Wilcken, Daniel A. Guthy, Andreas Lingel, Claudio Bomio-Confaglia, Rainer Machauer, Pascal Rigollier, Johannes Ottl, Dorothee Arz, Pascal Bernet, Gaëlle Desjonqueres, Solene Dussauge, Malika Kazic-Legueux, Marie-Anne Lozac’h, Christophe Mura, Mickaël Sorge, Milen Todorov, Nicolas Warin, Florence Zink, Hans Voshol, Frederic J. Zecri, Richard C. Sedrani, Nils Ostermann, Saskia M. Brachmann, Simona Cotesta
المصدر: Journal of Medicinal Chemistry. 65:16173-16203
بيانات النشر: American Chemical Society (ACS), 2022.
سنة النشر: 2022
مصطلحات موضوعية: Drug Discovery, Molecular Medicine
تدمد: 1520-4804
0022-2623
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ad7ccf3634960d3fbc0cb2fa59a10551
https://doi.org/10.1021/acs.jmedchem.2c01438
حقوق: CLOSED
رقم الأكسشن: edsair.doi...........ad7ccf3634960d3fbc0cb2fa59a10551
قاعدة البيانات: OpenAIRE