Clinical outcomes after colchicine overdose
العنوان: | Clinical outcomes after colchicine overdose |
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المؤلفون: | He Zhao, Mingjie Fu, Anwei Lu, Jie Zhao, Zhitao Li |
المصدر: | Medicine. 98:e16580 |
بيانات النشر: | Ovid Technologies (Wolters Kluwer Health), 2019. |
سنة النشر: | 2019 |
مصطلحات موضوعية: | Colchicine overdose, biology, Cell division, business.industry, Lethal dose, macromolecular substances, General Medicine, Pharmacology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Tubulin, chemistry, Microtubule, 030220 oncology & carcinogenesis, biology.protein, Distribution (pharmacology), Colchicine, Medicine, 030212 general & internal medicine, business, Intracellular |
الوصف: | Rationale:Colchicine can inhibit cell division and intracellular transport in affected organs by fixing intracellular tubulin and preventing its polymerization into microtubules. A lethal dose of colchicine is considered to be 0.8 mg/kg. The wide distribution of colchicine through 70% of the |
تدمد: | 1536-5964 0025-7974 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::af1c88a03cfc703ea916fae2f43a3a24 https://doi.org/10.1097/md.0000000000016580 |
حقوق: | OPEN |
رقم الأكسشن: | edsair.doi...........af1c88a03cfc703ea916fae2f43a3a24 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 15365964 00257974 |
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