Synthesis of 6‐Cycloalkyl‐2(3H)‐benzoxazolones and Benzoxathiazolones via 6‐Tri‐N‐butyltin Intermediates
| العنوان: | Synthesis of 6‐Cycloalkyl‐2(3H)‐benzoxazolones and Benzoxathiazolones via 6‐Tri‐N‐butyltin Intermediates |
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| المؤلفون: | Pascal Carato, Pascal Berthelot, S. Yous, Jacques Poupaert, Ziaeddine Moussavi, Nicolas Lebegue |
| المصدر: | Synthetic Communications. 34:2601-2609 |
| بيانات النشر: | Informa UK Limited, 2004. |
| سنة النشر: | 2004 |
| مصطلحات موضوعية: | Acylation, chemistry.chemical_compound, Tri-n-butyltin, chemistry, Reagent, Organic Chemistry, Tributyltin, Substrate (chemistry), Organic chemistry, Molecule, chemistry.chemical_element, Sulfur, Lewis acid catalysis |
| الوصف: | Friedel-Crafts acylation of highly activated aromatic nuclei is rendered difficult by the fact that extensive complexation of the substrate by the Lewis acid catalyst inevitably takes place, which deactivates more or less completely such reagents. 2(3H)-benzoxazolones and their sulfur bioisosters were chosen as model molecules in an effort to search for an efficient alternative method to the Friedel-Crafts reaction. 6-Cyclo-alkylcarbonyl-3-methyl-2(3H)-benzoxazolones and benzothiazolones which cannot be synthesized by classical Friedel-Crafts approach are expeditiously obtained via tributyltin intermediates to afford the desired compounds in good yields. |
| تدمد: | 1532-2432 0039-7911 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::b163741d6d9cf78250b9b8c39db406fc https://doi.org/10.1081/scc-200025620 |
| رقم الأكسشن: | edsair.doi...........b163741d6d9cf78250b9b8c39db406fc |
| قاعدة البيانات: | OpenAIRE |
PDF full text from Publisher | تدمد: | 15322432 00397911 |
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