The Importance of Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio in Predicting the Appearance of the Rectal Stenosis or Rectal Obstruction in Patients with Rectal Adenocarcinomas
| العنوان: | The Importance of Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio in Predicting the Appearance of the Rectal Stenosis or Rectal Obstruction in Patients with Rectal Adenocarcinomas |
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| المؤلفون: | Septimiu Voidazan, Nicolae Bacalbasa, Florentina Cristina Scarlat, Klara Brinzaniuc, Bogdan Andrei Suciu, Ioana Halmaciu, Vlad Vunvulea, Mircea Muresan, Calin Molnar |
| المصدر: | Revista de Chimie. 71:239-247 |
| بيانات النشر: | Revista de Chimie SRL, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | medicine.medical_specialty, Process equipment, business.industry, Materials Science (miscellaneous), Process Chemistry and Technology, Lymphocyte, General Engineering, Rectal stenosis, General Chemistry, General Medicine, Gastroenterology, General Biochemistry, Genetics and Molecular Biology, medicine.anatomical_structure, Rectal obstruction, Internal medicine, Materials Chemistry, medicine, In patient, Platelet, General Pharmacology, Toxicology and Pharmaceutics, Neutrophil to lymphocyte ratio, business |
| الوصف: | The purpose of this study was to establish a correlation between markers of inflammation and the risk of rectal stenosis or obstruction, in patients with rectal adenocarcinomas. We performed a retrospective observational study on 188 patients diagnosed with rectal adenocarcinomas. We attempted to establish a correlation between the neutrophils to lymphocyte ratio(NLR), platelet to lymphocyte ratio(PLR) levels and the presence of rectal stenosis or rectal obstruction. From 188 patients included in the study, 65 patients had stenotic tumors (34.57% of cases) and 10 patients had occlusive tumors (5.31% of cases). We obtained a statistically significant correlation between the blood levels of neutrophils, lymphocytes, platelets, and the existence of rectal stenosis. (p[0.05). The cutoff value of NLR that correlates with the presence of rectal stenosis was 2.5 (95% CI: 0.426-0.574, AUC: 0.500). As for PLR, the cutoff value correlated with the presence of rectal stenosis was 106,522 (95%CI: 0.428-0.575, AUC: 0.502). We established a statistically significant correlation between NLR, PLR and rectal obstruction (p[0.05). The cutoff value of the NLR that correlates with the presence of rectal obstruction was 4.633 (95%CI: 0.614-0.751, AUC: 0.685). As for PLR, the cutoff value correlated with the presence of rectal stenosis was 345.05 (95% CI: 0.673-0.803, AUC: 0.742). Our study shows that there is a statistically significant correlation between NLR and PLR and the risk of rectal obstruction in patients with adenocarcinomas. It is still necessary to conduct prospective studies on much larger lots of patients to determine the NLR and PLR values that can predict rectal stenosis as well as rectal obstruction. |
| تدمد: | 2668-8212 0034-7752 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::b244321223c4eb11a444662916ebd921 https://doi.org/10.37358/rc.20.2.7921 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi...........b244321223c4eb11a444662916ebd921 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 26688212 00347752 |
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