التفاصيل البيبلوغرافية
العنوان:
Novel inhibitors of the αvβ3 integrin—lead identification strategy
المؤلفون:
Peter Newham , Eleanor Henshaw , Philip A. MacFaul , Keith Oldham , Andrew David Morley , Neil Rankine , Christine M. Wood , David Elliot , Ken Page , Attilla Ting , Paul T. Sharpe
المصدر:
Bioorganic & Medicinal Chemistry Letters . 19:4832-4835
بيانات النشر:
Elsevier BV, 2009.
سنة النشر:
2009
مصطلحات موضوعية:
biology , Cell adhesion molecule , medicine.drug_class , Chemistry , Organic Chemistry , Clinical Biochemistry , Integrin , Pharmaceutical Science , Carboxamide , Biochemistry , In vitro , embryonic structures , Drug Discovery , cardiovascular system , medicine , biology.protein , Molecular Medicine , Structure–activity relationship , Potency , Binding site , Arginine binding , Molecular Biology
الوصف:
A novel approach to inhibition of the alphavbeta3 integrin is described, which uses compounds designed to generate nM potency without using the arginine binding site.
تدمد:
0960-894X
URL الوصول:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2c9ae033aabae6163e2ea27dfabe4eb https://doi.org/10.1016/j.bmcl.2009.06.041
حقوق:
CLOSED
رقم الأكسشن:
edsair.doi...........b2c9ae033aabae6163e2ea27dfabe4eb
قاعدة البيانات:
OpenAIRE
