Comparison of demographic features and prognosis between cardiogenic shock in patients with Chagas heart disease and other etiologies – Registry Of Acute Medical Emergencies in Brazil (ROAD)
| العنوان: | Comparison of demographic features and prognosis between cardiogenic shock in patients with Chagas heart disease and other etiologies – Registry Of Acute Medical Emergencies in Brazil (ROAD) |
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| المؤلفون: | Maria Cristina César, E.C Roque, H.B.B Balbao, Victor Araújo, Bruno Biselli, B.G Rizerio, Furlan, Alexandre de Matos Soeiro, Renato D. Lopes, R.S Pessoa, Road Brazil Registry, Mucio Tavares de Oliveira, E A Bocchi, M.P Wetten, R.L Teixeira, P.G.M.B Silva |
| المصدر: | European Heart Journal. 41 |
| بيانات النشر: | Oxford University Press (OUP), 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | medicine.medical_specialty, Orthopnea, Ejection fraction, Heart disease, business.industry, Cardiogenic shock, medicine.disease, Comorbidity, Heart failure, Emergency medicine, Epidemiology, medicine, Dobutamine, medicine.symptom, Cardiology and Cardiovascular Medicine, business, medicine.drug |
| الوصف: | Background Chagas disease is a chronic, systemic, parasitic infection caused by Trypanosoma cruzi, and a common cause of heart failure (HF) in Latin America. The incidence can be as high as 14% in endemic areas. The prognosis seems to be worse than other causes of HF, with mortality of up to 20%/year. Mortality and prognosis during the acute decompensation, however, are less studied. Purpose Compare differences between cardiogenic shock (CS) in patients with HF caused by chronic Chagas heart disease (ChHD) and those caused by other etiologies (non-ChHD). Methods We performed a multicentric, prospective, observational study of patients admitted with CS at 3 emergency departments in Brazil between January 2015 and December 2019. Baseline characteristics and intrahospital outcomes were obtained. Statistical analysis: The primary outcome was combined intra-hospital events (death, stroke, acute renal failure and bleeding). Comparison between groups was performed through Chi-squared and Student's T-test and the multivariate analysis by logistic regression, being p Results 856 patients with CS were included, 158 (18,5%) ChHD and 698 (81,5%) non-ChHD. Those with ChHD were younger (60.5±11.7 vs. 64.9±4.8 years old, p Conclusion To the best of our knowledge, this is the biggest registry with Chagasic patients in cardiogenic shock. They were younger and had less comorbidities, but were admitted with lower blood pressure, more symptoms and needed more inotropes in the first 24 hours. No difference in mortality or combined outcome was observed. Funding Acknowledgement Type of funding source: None |
| تدمد: | 1522-9645 0195-668X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::b49f9edb5f042c0fde1245e58dabf779 https://doi.org/10.1093/ehjci/ehaa946.1197 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi...........b49f9edb5f042c0fde1245e58dabf779 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15229645 0195668X |
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