Summary The successful management of invasive fungal infections continues to plague the clinician. They are associated with an unacceptably high morbidity and mortality, with reliable diagnostics a major issue. Although well described in the immunocompromised, especially haemato-oncology patients, there is no doubt that these infections are on the rise in the critically ill, intensive care patient. This article aims to examine and focus on the changing epidemiology, problems with diagnostics and the management of such life threatening sepsis.
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