Formulation and Characterization of Kaffir Lime Oil Nanoemulsion
| العنوان: | Formulation and Characterization of Kaffir Lime Oil Nanoemulsion |
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| المؤلفون: | Ghea Putri Christy, Dewa Ayu Arimurni, Made Dwi Pradipta Wahyudi, Ronny Martien, Woro Anindito Sri Tunjung |
| المصدر: | Biosciences, Biotechnology Research Asia. 14:915-922 |
| بيانات النشر: | Oriental Scientific Publishing Company, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Drug Discovery, complex mixtures, Agronomy and Crop Science, Biotechnology |
| الوصف: | Kaffir lime oil has many health benefits. However, an obstacle to its commercial use is oxidation during storage. Nanoemulsions (particulate colloidal systems) have been shown to be suitable carriers for lipophilic essential oil constituents due to amphipathic compounds that facilitate solubility. The objectives of this study were to formulate thermodynamically stable kaffir lime oil nanoemulsions and to investigate their physicochemical properties. Air-dried leaves of kaffir lime were subjected to steam distillation to obtain essential oil. Preparation of nanoemulsions was done using the spontaneous emulsification method. Tween 80 and propylene glycol were selected as surfactant mix components. The oil phase consisted of Miglyol 812 as a carrier oil for kaffir lime oil while double-distilled water was used in the aqueous phase. The best formula with transmittance above 95% and highest essential oil content was selected. It contained 20% of Tween 80, 10% of propylene glycol, 1.25% Miglyol 812, and 3.75% kaffir lime essential oil. This formula was then characterized and its thermodynamic stability determined. . The results showed that kaffir lime oil nanoemulsions were thermodynamically stable and robustly withstood variations in temperature, centrifugation, and long-term storage. Additionally, the nanoemulsions had low viscosity, which may facilitate its development as a pharmaceutical compound. |
| تدمد: | 2456-2602 0973-1245 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::b68201e6af9a634a922d9644d70abb25 https://doi.org/10.13005/bbra/2525 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi...........b68201e6af9a634a922d9644d70abb25 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 24562602 09731245 |
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